Provided by: Chunghwa Chemical Synthesis & Biotech Co., Ltd.

SEQ_NO

2

Date of announcement

2018/03/31

Time of announcement

16:35:41

Spokesman:

Chuan-Wen Chen

Title of Spokesman:

Vice President

Subject

Announcement of the Change of Chairman on Behalf of Subsidiary, Pharmaports, LLC

To which item it meets

paragraph 6

Date of events

2018/03/31

Statement

1. Date of occurrence of the change: 2018/03/31

2. Personnel: Chairman

3. Name and resume of the replaced person:

    Chih-Ping Yang

    Chairman, Pharmaports, LLC

4. Name and resume of the replacement:

    Denry J. Huang will be the acting Chairman from April 1 2018.

5. Type of the change (please enter: “resignation”, “position adjustment”, “dismissal”, “retirement”, ”death” or “new replacement” ): resignation

6. Reason for the change: resignation

7. Effective date: 2018/04/01

8. Any other matters that need to be specified: None